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An eight-year-old boy is one of just 11 people in the world with a rare genetic mutation.<br/><br/>Grayson, now eight, was put forward for blood tests when he was diagnosed with autism as a toddler.<br/><br/>He was then put on a trial after a meeting with his geneticist who looked at his genetic markers - including his nose, hair, feet and hands. <br/><br/>His family thought no more about it until they got a letter back last year to say he also has a single nucleotide duplication called Shank2.<br/><br/>This means he was born with a rare genetic mutation which changed the DNA alphabet within his gene. <br/><br/>His mum Rhiannon Bourne, 29, said there is \
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Get ready to be thrilled by the electrifying official trailer for the latest Marvel superhero sensation, \
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The top 30 simple things that make us smile include a kind gesture from a stranger, waking up on a sunny morning – and seeing an elderly couple holding hands.<br/><br/>A study of 2,000 adults found seeing a loved one get good news, receiving a surprise gift and getting a hug also feature on the list.<br/><br/>While others experience the same joy after getting into bed with freshly washed sheets, seeing an old friend and watching a puppy.<br/><br/>But for 46 per cent of people, simply having someone smile at you makes you feel happy, with 65 per cent of adults saying that it improves their mood.<br/><br/>That positive boost lasts for an average of more than 13 minutes, leaving them more likely to be kinder to others (37 per cent), more motivated (19 per cent) or make a bold decision (nine per cent).<br/><br/>Bupa Dental Care [https://www.bupa.co.uk/dental/dental-care] commissioned the research as part of National Smile Month, to highlight the benefits the friendly gesture can have.<br/><br/>However, an experiment saw just 21 per cent of adults return the friendly gesture from a stranger.<br/><br/>During a two-hour period, actress Zara Naeem smiled at 112 different people as they walked past her - with only 24 replying with the same expression.<br/><br/>Psychologist, Jo Hemmings, said: “When we smile, a number of psychological and physiological changes occur that impact both ourselves and those around us.<br/><br/>“Smiling releases endorphins, dopamine and serotonin – hormones which improve our mood and our sense of well-being – and also reduces cortisol, our stress hormone, making us feel less anxious and more relaxed.<br/><br/>“A genuine and spontaneous smile which reaches our eyes – known as the Duchenne smile – can also lower our blood pressure and boost our immune system, by increasing our production of white blood cells.<br/><br/>“Smiles also have a positive effect on those around us, by reinforcing friendship, kindness and social bonding as well as having a contagious effect, creating positivity in those on the receiving end of a smile.”<br/><br/>The research also found the average adult claims to smile at a stranger five times a week – but 16 per cent admit they rarely or never return the gesture.<br/><br/>Of these, a third blame it on simply being lost in their own thoughts and not paying attention to what is happening around them, while 20 per cent put it down to being in a rush.<br/><br/>But 27 per cent avoid smiling at others over fears they will ‘look weird’ and 14 per cent are too embarrassed.<br/><br/>However, when a stranger smiles at them, half of adults feel happy and 32 per cent feel uplifted.<br/><br/>Others feel comforted (11 per cent), ‘warm and fuzzy’ (15 per cent) and confident (11 per cent).<br/><br/>Less than one in 10 felt a negative emotion, such as confused (eight per cent) or sceptical (nine per cent). <br/><br/>Despite this, less than half (48 per cent) always return a smile from a stranger, with 34 per cent of those worried the grin was not meant for them.<br/><br/>While 32 per cent claim to be so surprised by the gesture that they don’t react quick enough.
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FDA advisers recommended that the new COVID-19 boosters for fall target the Omicron variant, which spread widely last winter, rather than trying to predict which subvariant will dominate in the coming months. Moderna, Pfizer, and Novavax have tested updated vaccines targeting the variant, which could be available in the fall if approved. Americans are advised to get a yearly COVID booster updated to match circulating strains, similar to the annual flu shot. Only around 22.5% of adults and 14% of children received the previous fall's booster targeting a different variant family. COVID remains deadlier than the flu based on a recent VA hospitalization analysis, despite lower current public concern.
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